Last review completed on
September 30th, 2020
Therapy Description

Ciclesonide is an inhaled corticosteroid used in the management of asthma. Ciclesonide is hypothesized to be helpful in the inflammation associated with SARS-CoV-2 infection, and it also may possess antiviral activity against SARS-CoV-2 in vitro. There are case reports suggesting that ciclesonide may inhibit proliferation of the virus and prevent progression to severe pneumonia when administered in the early or middle stages of infection.


There is insufficient evidence to support use of Ciclesonide for treatment of patients infected with SARS-CoV-2.

Clinical Circumstances
Level of Evidence
= Supporting use article = Neutral Article  = Contradicting use article

Step 1 - In vitro SARS CoV-1/2 and MERS-CoV
Step 2 - In vivo MERS-CoV Step 3 - In vivo SARS CoV-2
Therapy Tags